Methylenetetrahydrofolate C677T polymorphism and pre-eclamptic Egyptian women
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چکیده
منابع مشابه
Methylenetetrahydrofolate reductase C677T polymorphism and cognitive function in older women.
Homocysteine may play a causal role in cognitive decline. The authors analyzed the 5,10-methylenetetrahydrofolate reductase (MTHFR) C677T genotype, a correlate of plasma homocysteine levels, among 6,653 participants in the Study of Osteoporotic Fractures, a community-based, prospective cohort study of older women in four US states. During the years 1986-1998, the authors assessed whether the di...
متن کاملOriginal Contribution Methylenetetrahydrofolate Reductase C677T Polymorphism and Cognitive Function in Older Women
1 Department of Neurology, School of Medicine, University of California, San Francisco, San Francisco, CA. 2 Department of Epidemiology and Biostatistics, School of Medicine, University of California, San Francisco, San Francisco, CA. 3 Department of Medicine, School of Medicine, University of California, San Francisco, San Francisco, CA. 4 Department of Medicine, David Geffen School of Medicin...
متن کاملMethylenetetrahydrofolate Reductase C677T and A1298C Polymorphism in Iranian Women With Idiopathic Recurrent Pregnancy Losses
BACKGROUND Recurrent pregnancy loss (RPL) is a serious problem for pregnancy. There is evidence that vascular complications play a principal role in RPL. Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in folate metabolism. Polymorphisms (C677T, A1298C) of MTHFR gene are associated with decreased MTHFR activity. OBJECTIVES The aim of this study was to determine the association bet...
متن کاملEvaluation of the Association between the C677T Polymorphism of Methylenetetrahydrofolate Reductase Gene and Recurrent Spontaneous Abortion
Introduction: One factor known to cause thrombophilia in women with unexplained recurrent spontaneous abortion (RSA) is C677T polymorphism of methylenetetrahydrofolate reductase gene. This study aimed to determine the association between RSA and MTHFR C677T polymorphism in Iranian patients. Methods: In this case-control study, 30 patients with previous history of two or more consecutive unexpla...
متن کاملMethylenetetrahydrofolate reductase C677T polymorphism and breast cancer risk in Moroccan women.
BACKGROUND Methylenetetrahydrofolate (MTHFR) enzyme plays an important role in folate metabolism which is involved in DNA methylation, repair, and synthesis. OBJECTIVE We investigated if the MTHFR C677T polymorphism modulates the risk of developing breast cancer in Moroccan women. METHODS Genotyping was performed by PCR-RFLP method on a sample of 96 patients with breast cancer and 117 contr...
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ژورنال
عنوان ژورنال: Middle East Fertility Society Journal
سال: 2012
ISSN: 1110-5690
DOI: 10.1016/j.mefs.2011.09.005